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DNA Cell Biol. 1999 Jul; 5(4):282-93. 2006 Aug; 44(2):420-9. Vice Chancellor, UC San Diego Health Sciences. Dr. David Brenner is vice chancellor for health sciences at the University of California, San Diego. In this role, he leads the School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California, San Diego, and UC San Diego Health. J Biol Chem. The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Zhong Z, Tsukada S, Rehman H, Parsons CJ, Theruvath TP, Rippe RA. Association between serum interleukin-6 concentrations and mortality in older adults: the Rancho Bernardo study. Hellerbrand C, Stefanovic B, Giordano F, Burchardt ER. 2002 Nov; 70(11):6294-301. Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats. Miller AC, Rivas R, Tesoro L, Kovalenko G, Kovaric N, Pavlovic P. 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USC undermined our ability to do research. Am J Physiol. Gastroenterology. Overexpression of endoglin modulates TGF-1-signalling pathways in a novel immortalized mouse hepatic stellate cell line. 2005 Feb; 115(2):209-18. 2003 Feb; 37(2):267-76. 2015 Nov-Dec; 49 Suppl 1:S25-7. Hepatology. Brain Commun. Hepatology. Nat Rev Gastroenterol Hepatol. Westwick JK, Fleckenstein J, Yin M, Yang SQ, Bradham CA. Liver regeneration is suppressed in small-for-size liver grafts after transplantation: involvement of c-Jun N-terminal kinase, cyclin D1, and defective energy supply. Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease. Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease. Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury. Am J Pathol. J Biol Chem. Transforming growth factor-alpha stimulates proto-oncogene c-jun expression and a mitogenic program in primary cultures of adult rat hepatocytes. J Hepatol. Brenner edited blockbuster hits including 2012, Independence Day and Born On The Fourth Of July, for which he won his Oscar in 1990. Study of loneliness and wisdom in 482 middle-aged and oldest-old adults: a comparison between people in Cilento, Italy and San Diego, USA. Surgery. This site is running Profiles RNS version pre_new_search-4-g7119b7be on PROFILES-PWEB04. J Gastroenterol Hepatol. Gastroenterology. We lose people all of the time. Science. Study of factors causing excess protoporphyrin accumulation in cultured skin fibroblasts from patients with protoporphyria. Hattori M, Tugores A, Westwick JK, Veloz L. Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity. Proc Natl Acad Sci U S A. Cell Death Differ. Semin Liver Dis. Signal transduction during liver regeneration. 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